There is no general '4-pot Brembo' as there are many types and they all come with different disk sizes as well...
To my surprise I did manage the 15" spacesaver around my former 302x32 disk with the huge 928S 4-pot brembos, so my guess is they clear more easily than most other rims, but no guarentees whatsoever.
Rears usually always clear. I now have 299x24 with the 993 rear caliper and that clears fine as you can see in the picture above.
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